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4d9q

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{{STRUCTURE_4d9q| PDB=4d9q | SCENE= }}
 
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===Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D===
 
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{{ABSTRACT_PUBMED_22362762}}
 
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==About this Structure==
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==Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D==
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[[4d9q]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Crab-eating_macaque Crab-eating macaque] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D9Q OCA].
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<StructureSection load='4d9q' size='340' side='right'caption='[[4d9q]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
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== Structural highlights ==
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==Reference==
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<table><tr><td colspan='2'>[[4d9q]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Macaca_mulatta Macaca mulatta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D9Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D9Q FirstGlance]. <br>
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<ref group="xtra">PMID:022362762</ref><references group="xtra"/><references/>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
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[[Category: Crab-eating macaque]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Human]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d9q OCA], [https://pdbe.org/4d9q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d9q RCSB], [https://www.ebi.ac.uk/pdbsum/4d9q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d9q ProSAT]</span></td></tr>
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[[Category: Murray, J M.]]
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</table>
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[[Category: Wiesmann, C.]]
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== Function ==
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[[Category: Antibody]]
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[https://www.uniprot.org/uniprot/F6YBP7_MACMU F6YBP7_MACMU]
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[[Category: Chymotrypsin]]
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__TOC__
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[[Category: Complement]]
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</StructureSection>
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[[Category: Exosite]]
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[[Category: Homo sapiens]]
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[[Category: Fab]]
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[[Category: Large Structures]]
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[[Category: Factor d]]
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[[Category: Macaca mulatta]]
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[[Category: Hydrolase-immune system complex]]
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[[Category: Murray JM]]
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[[Category: Protease]]
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[[Category: Wiesmann C]]

Current revision

Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D

PDB ID 4d9q

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