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4dau

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[[Image:4dau.jpg|left|200px]]
 
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==Structure of 14-3-3 sigma in complex with PADI6 14-3-3 binding motif I==
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The line below this paragraph, containing "STRUCTURE_4dau", creates the "Structure Box" on the page.
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<StructureSection load='4dau' size='340' side='right'caption='[[4dau]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4dau]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DAU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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{{STRUCTURE_4dau| PDB=4dau | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dau OCA], [https://pdbe.org/4dau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dau RCSB], [https://www.ebi.ac.uk/pdbsum/4dau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dau ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
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===Structure of 14-3-3 sigma in complex with PADI6 14-3-3 binding motif I===
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==See Also==
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*[[14-3-3 protein 3D structures|14-3-3 protein 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22634725 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22634725}}
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==About this Structure==
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[[4dau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DAU OCA].
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==Reference==
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<ref group="xtra">PMID:022634725</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein-arginine deiminase]]
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[[Category: Large Structures]]
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[[Category: Ottmann, C.]]
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[[Category: Ottmann C]]
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[[Category: Rose, M.]]
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[[Category: Rose M]]
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[[Category: Rose, R.]]
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[[Category: Rose R]]
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[[Category: 14-3-3 fold]]
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[[Category: Protein-protein interaction]]
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[[Category: Signaling protein-protein binding complex]]
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Current revision

Structure of 14-3-3 sigma in complex with PADI6 14-3-3 binding motif I

PDB ID 4dau

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