This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4dd8
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==ADAM-8 metalloproteinase domain with bound batimastat== | |
| + | <StructureSection load='4dd8' size='340' side='right'caption='[[4dd8]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4dd8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DD8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BAT:4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE'>BAT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dd8 OCA], [https://pdbe.org/4dd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dd8 RCSB], [https://www.ebi.ac.uk/pdbsum/4dd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dd8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ADAM8_HUMAN ADAM8_HUMAN] Possible involvement in extravasation of leukocytes. | ||
| - | + | ==See Also== | |
| - | + | *[[A Disintegrin And Metalloproteinase 3D structures|A Disintegrin And Metalloproteinase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Caspers N]] | ||
| + | [[Category: Chrencik JE]] | ||
| + | [[Category: Day JE]] | ||
| + | [[Category: Fischer DH]] | ||
| + | [[Category: Hall T]] | ||
| + | [[Category: Kiefer JR]] | ||
| + | [[Category: Krahn JM]] | ||
| + | [[Category: Moon AF]] | ||
| + | [[Category: Pauley AM]] | ||
| + | [[Category: Pegg LE]] | ||
| + | [[Category: Shieh HS]] | ||
| + | [[Category: Tomasselli AG]] | ||
| + | [[Category: Williams JM]] | ||
| + | [[Category: Zack MD]] | ||
Current revision
ADAM-8 metalloproteinase domain with bound batimastat
| |||||||||||
Categories: Homo sapiens | Large Structures | Caspers N | Chrencik JE | Day JE | Fischer DH | Hall T | Kiefer JR | Krahn JM | Moon AF | Pauley AM | Pegg LE | Shieh HS | Tomasselli AG | Williams JM | Zack MD
