4e5o

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[[Image:4e5o.jpg|left|200px]]
 
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==Crystal structure of mouse thymidylate synthase in complex with dUMP==
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The line below this paragraph, containing "STRUCTURE_4e5o", creates the "Structure Box" on the page.
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<StructureSection load='4e5o' size='340' side='right'caption='[[4e5o]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4e5o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ihh 3ihh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E5O FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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{{STRUCTURE_4e5o| PDB=4e5o | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e5o OCA], [https://pdbe.org/4e5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e5o RCSB], [https://www.ebi.ac.uk/pdbsum/4e5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e5o ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).
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===Crystal structure of mouse thymidylate synthase in complex with dUMP===
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==See Also==
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*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4e5o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ihh 3ihh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E5O OCA].
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Thymidylate synthase]]
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[[Category: Ciesla J]]
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[[Category: Ciesla, J.]]
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[[Category: Dowiercial A]]
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[[Category: Dowiercial, A.]]
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[[Category: Fraczyk T]]
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[[Category: Fraczyk, T.]]
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[[Category: Jarmula A]]
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[[Category: Jarmula, A.]]
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[[Category: Rode W]]
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[[Category: Rode, W.]]
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[[Category: Rypniewski W]]
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[[Category: Rypniewski, W.]]
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[[Category: Sokolowska M]]
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[[Category: Sokolowska, M.]]
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[[Category: Methyltransferase]]
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[[Category: Nucleotide biosynthesis]]
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[[Category: Protein-ligand complex]]
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[[Category: Transferase]]
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Current revision

Crystal structure of mouse thymidylate synthase in complex with dUMP

PDB ID 4e5o

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OCA

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