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4ef0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4ef0 is ON HOLD Authors: Vinaik, R., Kozlov, G., Gehring, K. Description: Crystal Structure of the first catalytic domain of protein disulfide isom...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the first catalytic domain of protein disulfide isomerase P5== | |
| - | + | <StructureSection load='4ef0' size='340' side='right'caption='[[4ef0]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ef0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EF0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ef0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ef0 OCA], [https://pdbe.org/4ef0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ef0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ef0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ef0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PDIA6_HUMAN PDIA6_HUMAN] May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.<ref>PMID:15466936</ref> <ref>PMID:12204115</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gehring K]] | ||
| + | [[Category: Kozlov G]] | ||
| + | [[Category: Vinaik R]] | ||
Current revision
Crystal Structure of the first catalytic domain of protein disulfide isomerase P5
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