This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4ey4
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:4ey4.png|left|200px]] | ||
| - | + | ==Crystal Structure of Recombinant Human Acetylcholinesterase in the Apo state== | |
| + | <StructureSection load='4ey4' size='340' side='right'caption='[[4ey4]], [[Resolution|resolution]] 2.16Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4ey4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EY4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.156Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ey4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ey4 OCA], [https://pdbe.org/4ey4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ey4 RCSB], [https://www.ebi.ac.uk/pdbsum/4ey4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ey4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACES_HUMAN ACES_HUMAN] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.<ref>PMID:2714437</ref> <ref>PMID:1748670</ref> <ref>PMID:1517212</ref> <ref>PMID:11985878</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | |
| - | + | *[[Human Acetylcholinesterase|Human Acetylcholinesterase]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | [[ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Burshteyn | + | [[Category: Large Structures]] |
| - | [[Category: Cassidy | + | [[Category: Burshteyn F]] |
| - | [[Category: Cheung | + | [[Category: Cassidy M]] |
| - | [[Category: Franklin | + | [[Category: Cheung J]] |
| - | [[Category: Gary | + | [[Category: Franklin M]] |
| - | [[Category: Height | + | [[Category: Gary E]] |
| - | [[Category: Love | + | [[Category: Height J]] |
| - | [[Category: Rudolph | + | [[Category: Love J]] |
| - | + | [[Category: Rudolph M]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Recombinant Human Acetylcholinesterase in the Apo state
| |||||||||||
Categories: Homo sapiens | Large Structures | Burshteyn F | Cassidy M | Cheung J | Franklin M | Gary E | Height J | Love J | Rudolph M
