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4f3f

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[[Image:4f3f.jpg|left|200px]]
 
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{{STRUCTURE_4f3f| PDB=4f3f | SCENE= }}
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==Crystal Structure of Msln7-64 MORAb-009 FAB complex==
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<StructureSection load='4f3f' size='340' side='right'caption='[[4f3f]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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===Crystal Structure of Msln7-64 MORAb-009 FAB complex===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4f3f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F3F FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
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[[4f3f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3F OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f3f OCA], [https://pdbe.org/4f3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f3f RCSB], [https://www.ebi.ac.uk/pdbsum/4f3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f3f ProSAT]</span></td></tr>
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[[Category: Escherichia coli]]
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer.
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== Function ==
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[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Membrane-anchored forms may play a role in cellular adhesion.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Esser, L.]]
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[[Category: Large Structures]]
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[[Category: Ma, J.]]
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[[Category: Mus musculus]]
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[[Category: Pastan, I.]]
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[[Category: Esser L]]
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[[Category: Tang, W K.]]
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[[Category: Ma J]]
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[[Category: Xia, D.]]
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[[Category: Pastan I]]
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[[Category: Antibody fab]]
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[[Category: Tang WK]]
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[[Category: Immune system]]
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[[Category: Xia D]]
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[[Category: Mesothelin]]
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[[Category: Recognize mesothelin]]
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Current revision

Crystal Structure of Msln7-64 MORAb-009 FAB complex

PDB ID 4f3f

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