This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4f3f
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4f3f| PDB=4f3f | SCENE= }} | ||
| - | ===Crystal Structure of Msln7-64 MORAb-009 FAB complex=== | ||
| - | == | + | ==Crystal Structure of Msln7-64 MORAb-009 FAB complex== |
| - | [[http://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN | + | <StructureSection load='4f3f' size='340' side='right'caption='[[4f3f]], [[Resolution|resolution]] 2.65Å' scene=''> |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4f3f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F3F FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f3f OCA], [https://pdbe.org/4f3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f3f RCSB], [https://www.ebi.ac.uk/pdbsum/4f3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f3f ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | + | == Disease == | |
| - | + | [https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. | |
| - | <references | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Membrane-anchored forms may play a role in cellular adhesion.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: Esser | + | <references/> |
| - | [[Category: Ma | + | __TOC__ |
| - | [[Category: Pastan | + | </StructureSection> |
| - | [[Category: Tang | + | [[Category: Homo sapiens]] |
| - | [[Category: Xia | + | [[Category: Large Structures]] |
| - | + | [[Category: Mus musculus]] | |
| - | + | [[Category: Esser L]] | |
| - | + | [[Category: Ma J]] | |
| - | + | [[Category: Pastan I]] | |
| + | [[Category: Tang WK]] | ||
| + | [[Category: Xia D]] | ||
Current revision
Crystal Structure of Msln7-64 MORAb-009 FAB complex
| |||||||||||
Categories: Homo sapiens | Large Structures | Mus musculus | Esser L | Ma J | Pastan I | Tang WK | Xia D
