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4f8b

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[[Image:4f8b.png|left|200px]]
 
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{{STRUCTURE_4f8b| PDB=4f8b | SCENE= }}
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==Crystal Structure of the Covalent Thioimide Intermediate of Unimodular Nitrile Reductase QueF==
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<StructureSection load='4f8b' size='340' side='right'caption='[[4f8b]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Crystal Structure of the Covalent Thioimide Intermediate of Unimodular Nitrile Reductase QueF===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4f8b]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F8B FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22787148}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.502&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GD1:2-AMINO-5-[(Z)-IMINOMETHYL]-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>GD1</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f8b OCA], [https://pdbe.org/4f8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f8b RCSB], [https://www.ebi.ac.uk/pdbsum/4f8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f8b ProSAT]</span></td></tr>
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[[4f8b]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis Bacillus subtilis subsp. subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F8B OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/QUEF_BACSU QUEF_BACSU] Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the queuosine pathway.<ref>PMID:15767583</ref> <ref>PMID:17929836</ref>
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<ref group="xtra">PMID:022787148</ref><references group="xtra"/>
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== References ==
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[[Category: Bacillus subtilis subsp. subtilis]]
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<references/>
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[[Category: Stec, B.]]
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__TOC__
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[[Category: Swairjo, M A.]]
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</StructureSection>
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[[Category: 7-cyano-7-deazaguanine]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Beta barrel]]
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[[Category: Large Structures]]
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[[Category: Nadph]]
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[[Category: Stec B]]
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[[Category: Oxidoreductase]]
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[[Category: Swairjo MA]]
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[[Category: Protein thioimide complex]]
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[[Category: Pterin binding fold]]
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[[Category: Trna modification enzyme]]
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[[Category: Tunnel fold]]
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Current revision

Crystal Structure of the Covalent Thioimide Intermediate of Unimodular Nitrile Reductase QueF

PDB ID 4f8b

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