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4fdi

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[[Image:4fdi.png|left|200px]]
 
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{{STRUCTURE_4fdi| PDB=4fdi | SCENE= }}
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==The molecular basis of mucopolysaccharidosis IV A==
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<StructureSection load='4fdi' size='340' side='right'caption='[[4fdi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4fdi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FDI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FDI FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=DDZ:3,3-DIHYDROXY+L-ALANINE'>DDZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fdi OCA], [https://pdbe.org/4fdi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fdi RCSB], [https://www.ebi.ac.uk/pdbsum/4fdi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fdi ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/GALNS_HUMAN GALNS_HUMAN] Mucopolysaccharidosis type 4A. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/GALNS_HUMAN GALNS_HUMAN]
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===The molecular basis of mucopolysaccharidosis IV A===
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==See Also==
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*[[Sulfatase 3D structures|Sulfatase 3D structures]]
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{{ABSTRACT_PUBMED_22940367}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[4fdi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FDI OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: N-acetylgalactosamine-6-sulfatase]]
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[[Category: Large Structures]]
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[[Category: Garman, S C.]]
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[[Category: Garman SC]]
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[[Category: Rivera-Colon, Y.]]
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[[Category: Rivera-Colon Y]]
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[[Category: Enzyme replacement therapy]]
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[[Category: Formylglycine]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Lysosomal enzyme]]
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[[Category: N-linked glycosylation]]
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[[Category: Sulfatase]]
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Current revision

The molecular basis of mucopolysaccharidosis IV A

PDB ID 4fdi

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