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4fee

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[[Image:4fee.png|left|200px]]
 
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{{STRUCTURE_4fee| PDB=4fee | SCENE= }}
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==High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal B==
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<StructureSection load='4fee' size='340' side='right'caption='[[4fee]], [[Resolution|resolution]] 1.13&Aring;' scene=''>
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===High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal B===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4fee]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactiplantibacillus_plantarum_JDM1 Lactiplantibacillus plantarum JDM1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FEE FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22730460}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.13&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>, <scene name='pdbligand=TDM:2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TDM</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fee OCA], [https://pdbe.org/4fee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fee RCSB], [https://www.ebi.ac.uk/pdbsum/4fee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fee ProSAT]</span></td></tr>
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[[4fee]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_plantarum Lactobacillus plantarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEE OCA].
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</table>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:022730460</ref><references group="xtra"/>
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[[Category: Lactiplantibacillus plantarum JDM1]]
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[[Category: Lactobacillus plantarum]]
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[[Category: Large Structures]]
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[[Category: Pyruvate oxidase]]
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[[Category: Ficner R]]
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[[Category: Ficner, R.]]
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[[Category: Koers E]]
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[[Category: Koers, E.]]
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[[Category: Luedtke S]]
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[[Category: Luedtke, S.]]
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[[Category: Meyer D]]
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[[Category: Meyer, D.]]
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[[Category: Neumann P]]
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[[Category: Neumann, P.]]
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[[Category: Sheldrick GM]]
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[[Category: Sheldrick, G M.]]
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[[Category: Sjuts H]]
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[[Category: Sjuts, H.]]
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[[Category: Tittmann K]]
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[[Category: Tittmann, K.]]
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[[Category: Carbanion]]
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[[Category: Oxidation-reduction]]
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[[Category: Oxidoreductase]]
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[[Category: Reaction intermediate]]
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[[Category: Structure activity relationship]]
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[[Category: Thiamine diphosphate]]
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[[Category: Umpolung]]
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Current revision

High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal B

PDB ID 4fee

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