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4fev
From Proteopedia
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| - | {{STRUCTURE_4fev| PDB=4fev | SCENE= }} | ||
| - | ===Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP1=== | ||
| - | {{ABSTRACT_PUBMED_23758273}} | ||
| - | == | + | ==Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP1== |
| - | [[4fev]] is a 6 chain structure with sequence from [ | + | <StructureSection load='4fev' size='340' side='right'caption='[[4fev]], [[Resolution|resolution]] 1.89Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fev]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii_AYE Acinetobacter baumannii AYE]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FEV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PP1:1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE'>PP1</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fev OCA], [https://pdbe.org/4fev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fev RCSB], [https://www.ebi.ac.uk/pdbsum/4fev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fev ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B0VD92_ACIBY B0VD92_ACIBY] | ||
| - | == | + | ==See Also== |
| - | < | + | *[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]] |
| - | [[Category: Acinetobacter baumannii | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Anderson | + | [[Category: Acinetobacter baumannii AYE]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Egorova | + | [[Category: Anderson WF]] |
| - | [[Category: Evdokimova | + | [[Category: Di Leo R]] |
| - | + | [[Category: Egorova O]] | |
| - | [[Category: Minasov | + | [[Category: Evdokimova E]] |
| - | [[Category: Savchenko | + | [[Category: Minasov G]] |
| - | [[Category: Shakya | + | [[Category: Savchenko A]] |
| - | [[Category: Spanogiannopoulos | + | [[Category: Shakya T]] |
| - | [[Category: Stogios | + | [[Category: Spanogiannopoulos P]] |
| - | [[Category: Wawrzak | + | [[Category: Stogios PJ]] |
| - | [[Category: Wright | + | [[Category: Wawrzak Z]] |
| - | + | [[Category: Wright GD]] | |
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Current revision
Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP1
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