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4fhx

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[[Image:4fhx.jpg|left|200px]]
 
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{{STRUCTURE_4fhx| PDB=4fhx | SCENE= }}
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==Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - H336N mutant bound to MgATP==
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<StructureSection load='4fhx' size='340' side='right'caption='[[4fhx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4fhx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FHX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fhx OCA], [https://pdbe.org/4fhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fhx RCSB], [https://www.ebi.ac.uk/pdbsum/4fhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fhx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CID1_SCHPO CID1_SCHPO] Involved in cell cycle arrest where in association with crb2/rhp9 and chk1 it inhibits unscheduled mitosis.
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===Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - H336N mutant bound to MgATP===
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==See Also==
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*[[Poly(A) RNA polymerase|Poly(A) RNA polymerase]]
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{{ABSTRACT_PUBMED_22885303}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[4fhx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHX OCA].
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[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Lunde BM]]
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==Reference==
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[[Category: Magler I]]
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<ref group="xtra">PMID:022885303</ref><references group="xtra"/>
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[[Category: Meinhart A]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: Lunde, B M.]]
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[[Category: Magler, I.]]
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[[Category: Meinhart, A.]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Transferase]]
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Current revision

Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - H336N mutant bound to MgATP

PDB ID 4fhx

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