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4fl6
From Proteopedia
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==Crystal structure of the complex of the 3-MBT repeat domain of L3MBTL3 and UNC1215== | ==Crystal structure of the complex of the 3-MBT repeat domain of L3MBTL3 and UNC1215== | ||
| - | <StructureSection load='4fl6' size='340' side='right' caption='[[4fl6]], [[Resolution|resolution]] 2.55Å' scene=''> | + | <StructureSection load='4fl6' size='340' side='right'caption='[[4fl6]], [[Resolution|resolution]] 2.55Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4fl6]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4fl6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FL6 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=UWN:[2-(PHENYLAMINO)BENZENE-1,4-DIYL]BIS{[4-(PYRROLIDIN-1-YL)PIPERIDIN-1-YL]METHANONE}'>UWN</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=UWN:[2-(PHENYLAMINO)BENZENE-1,4-DIYL]BIS{[4-(PYRROLIDIN-1-YL)PIPERIDIN-1-YL]METHANONE}'>UWN</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fl6 OCA], [https://pdbe.org/4fl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fl6 RCSB], [https://www.ebi.ac.uk/pdbsum/4fl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fl6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/LMBL3_HUMAN LMBL3_HUMAN] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity). |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Brown | + | [[Category: Bountra C]] |
| - | [[Category: Dong | + | [[Category: Brown PJ]] |
| - | [[Category: Edwards | + | [[Category: Dong A]] |
| - | [[Category: Frye | + | [[Category: Edwards AM]] |
| - | [[Category: Graslund | + | [[Category: Frye SV]] |
| - | [[Category: Ingerman | + | [[Category: Graslund S]] |
| - | [[Category: Ravichandran | + | [[Category: Ingerman LA]] |
| - | + | [[Category: Ravichandran M]] | |
| - | [[Category: Tempel | + | [[Category: Tempel W]] |
| - | [[Category: Zhong | + | [[Category: Zhong N]] |
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Current revision
Crystal structure of the complex of the 3-MBT repeat domain of L3MBTL3 and UNC1215
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Brown PJ | Dong A | Edwards AM | Frye SV | Graslund S | Ingerman LA | Ravichandran M | Tempel W | Zhong N
