This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4fo2
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4fo2 is ON HOLD Authors: Cody, V., Pace, J., Nawar, H., Liang, S., Connell, T., Hajishengallis, G. Description: Heat-labile enterotoxin LT-IIb-B5(T...) |
|||
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Heat-labile enterotoxin LT-IIb-B5(T13I) mutant== | |
| - | + | <StructureSection load='4fo2' size='340' side='right'caption='[[4fo2]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4fo2]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FO2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fo2 OCA], [https://pdbe.org/4fo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fo2 RCSB], [https://www.ebi.ac.uk/pdbsum/4fo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fo2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/E2BB_ECOLX E2BB_ECOLX] The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cody V]] | ||
| + | [[Category: Connell T]] | ||
| + | [[Category: Hajishengallis G]] | ||
| + | [[Category: Liang S]] | ||
| + | [[Category: Nawar H]] | ||
| + | [[Category: Pace J]] | ||
Current revision
Heat-labile enterotoxin LT-IIb-B5(T13I) mutant
| |||||||||||
