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4fuk

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==Aminopeptidase from Trypanosoma brucei==
==Aminopeptidase from Trypanosoma brucei==
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<StructureSection load='4fuk' size='340' side='right' caption='[[4fuk]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='4fuk' size='340' side='right'caption='[[4fuk]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tryb2 Tryb2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FUK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fuk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FUK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tb10.61.1210, Tb11.1240 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=999953 TRYB2])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fuk OCA], [https://pdbe.org/4fuk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fuk RCSB], [https://www.ebi.ac.uk/pdbsum/4fuk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fuk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fuk OCA], [http://pdbe.org/4fuk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fuk RCSB], [http://www.ebi.ac.uk/pdbsum/4fuk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fuk ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q4FKC0_TRYB2 Q4FKC0_TRYB2]] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) (By similarity).[HAMAP-Rule:MF_03174]
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[https://www.uniprot.org/uniprot/Q4FKC0_TRYB2 Q4FKC0_TRYB2] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) (By similarity).[HAMAP-Rule:MF_03174]
==See Also==
==See Also==
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*[[Aminopeptidase|Aminopeptidase]]
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Methionyl aminopeptidase]]
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[[Category: Large Structures]]
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[[Category: Tryb2]]
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[[Category: Trypanosoma brucei brucei TREU927]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bakkouri, M El]]
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[[Category: Bountra C]]
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[[Category: Bountra, C]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M]]
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[[Category: El Bakkouri M]]
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[[Category: Graslund, S]]
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[[Category: Graslund S]]
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[[Category: Hui, R]]
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[[Category: Hui R]]
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[[Category: Lin, Y H]]
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[[Category: Lin YH]]
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[[Category: Loppnau, P]]
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[[Category: Loppnau P]]
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[[Category: Osman, K T]]
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[[Category: Osman KT]]
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[[Category: Structural genomic]]
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[[Category: Tempel W]]
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[[Category: Tempel, W]]
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[[Category: Hydrolase]]
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[[Category: Sgc]]
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Current revision

Aminopeptidase from Trypanosoma brucei

PDB ID 4fuk

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