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4gd7
From Proteopedia
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| - | {{STRUCTURE_4gd7| PDB=4gd7 | SCENE= }} | ||
| - | ===Wild-Type Human Thymidylate Synthase with bound Purpurogallin=== | ||
| - | == | + | ==Wild-Type Human Thymidylate Synthase with bound Purpurogallin== |
| - | [[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN | + | <StructureSection load='4gd7' size='340' side='right'caption='[[4gd7]], [[Resolution|resolution]] 2.29Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4gd7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GD7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TIY:2,3,4,6-TETRAHYDROXY-5H-BENZO[7]ANNULEN-5-ONE'>TIY</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gd7 OCA], [https://pdbe.org/4gd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gd7 RCSB], [https://www.ebi.ac.uk/pdbsum/4gd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gd7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | <references | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Celeste | + | [[Category: Celeste LR]] |
| - | [[Category: Lebioda | + | [[Category: Lebioda L]] |
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Current revision
Wild-Type Human Thymidylate Synthase with bound Purpurogallin
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