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4gis

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(New page: '''Unreleased structure''' The entry 4gis is ON HOLD Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Gl...)
Current revision (15:48, 14 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 4gis is ON HOLD
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==crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)==
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<StructureSection load='4gis' size='340' side='right'caption='[[4gis]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gis]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_harveyi_1DA3 Vibrio harveyi 1DA3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GIS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAE:MALEIC+ACID'>MAE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gis OCA], [https://pdbe.org/4gis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gis RCSB], [https://www.ebi.ac.uk/pdbsum/4gis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gis ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IMAND_VIBH1 IMAND_VIBH1] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref>
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Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Washington, E., Scott Glenn, A., Chowdhury, S., Evans, B., Hammonds, J., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
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==See Also==
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*[[Enolase 3D structures|Enolase 3D structures]]
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Description: crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Vibrio harveyi 1DA3]]
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[[Category: Al Obaidi NF]]
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[[Category: Almo SC]]
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[[Category: Bhosle R]]
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[[Category: Chowdhury S]]
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[[Category: Evans B]]
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[[Category: Gerlt JA]]
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[[Category: Hammonds J]]
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[[Category: Hillerich B]]
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[[Category: Imker HJ]]
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[[Category: Love J]]
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[[Category: Morisco LL]]
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[[Category: Scott Glenn A]]
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[[Category: Seidel RD]]
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[[Category: Sojitra S]]
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[[Category: Toro R]]
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[[Category: Vetting MW]]
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[[Category: Washington E]]
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[[Category: Wasserman SR]]

Current revision

crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)

PDB ID 4gis

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