4gis

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[[Image:4gis.jpg|left|200px]]
 
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{{STRUCTURE_4gis| PDB=4gis | SCENE= }}
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==crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)==
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<StructureSection load='4gis' size='340' side='right'caption='[[4gis]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gis]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_harveyi_1DA3 Vibrio harveyi 1DA3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GIS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAE:MALEIC+ACID'>MAE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gis OCA], [https://pdbe.org/4gis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gis RCSB], [https://www.ebi.ac.uk/pdbsum/4gis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gis ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IMAND_VIBH1 IMAND_VIBH1] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref>
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===crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)===
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==See Also==
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*[[Enolase 3D structures|Enolase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[4gis]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GIS OCA].
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__TOC__
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[[Category: Vibrio harveyi]]
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</StructureSection>
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[[Category: Almo, S C.]]
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[[Category: Large Structures]]
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[[Category: Bhosle, R.]]
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[[Category: Vibrio harveyi 1DA3]]
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[[Category: Chowdhury, S.]]
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[[Category: Al Obaidi NF]]
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[[Category: EFI, Enzyme Function Initiative.]]
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[[Category: Almo SC]]
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[[Category: Evans, B.]]
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[[Category: Bhosle R]]
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[[Category: Gerlt, J A.]]
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[[Category: Chowdhury S]]
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[[Category: Glenn, A Scott.]]
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[[Category: Evans B]]
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[[Category: Hammonds, J.]]
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[[Category: Gerlt JA]]
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[[Category: Hillerich, B.]]
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[[Category: Hammonds J]]
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[[Category: Imker, H J.]]
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[[Category: Hillerich B]]
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[[Category: Love, J.]]
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[[Category: Imker HJ]]
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[[Category: Morisco, L L.]]
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[[Category: Love J]]
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[[Category: Obaidi, N F.Al.]]
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[[Category: Morisco LL]]
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[[Category: Seidel, R D.]]
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[[Category: Scott Glenn A]]
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[[Category: Sojitra, S.]]
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[[Category: Seidel RD]]
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[[Category: Toro, R.]]
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[[Category: Sojitra S]]
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[[Category: Vetting, M W.]]
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[[Category: Toro R]]
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[[Category: Washington, E.]]
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[[Category: Vetting MW]]
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[[Category: Wasserman, S R.]]
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[[Category: Washington E]]
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[[Category: Efi]]
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[[Category: Wasserman SR]]
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[[Category: Enolase]]
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[[Category: Enzyme function initiative]]
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[[Category: Lyase]]
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[[Category: Putative mannonate dehydratase]]
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[[Category: Structural genomic]]
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Current revision

crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)

PDB ID 4gis

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