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4glf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of methylthioadenosine phosphorylase sourced from an antarctic soil metagenomic library== | |
| + | <StructureSection load='4glf' size='340' side='right'caption='[[4glf]], [[Resolution|resolution]] 1.98Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4glf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Uncultured_bacterium Uncultured bacterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GLF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4glf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4glf OCA], [https://pdbe.org/4glf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4glf RCSB], [https://www.ebi.ac.uk/pdbsum/4glf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4glf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/C6KFA4_9BACT C6KFA4_9BACT] Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963] | ||
| - | + | ==See Also== | |
| - | + | *[[5'-deoxy-5'-methylthioadenosine phosphorylase 3D structures|5'-deoxy-5'-methylthioadenosine phosphorylase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Uncultured bacterium]] | ||
| + | [[Category: Bartasun P]] | ||
| + | [[Category: Bujacz A]] | ||
| + | [[Category: Bujacz G]] | ||
| + | [[Category: Cieslinski H]] | ||
Current revision
Crystal structure of methylthioadenosine phosphorylase sourced from an antarctic soil metagenomic library
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