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4gmh

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==Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase==
==Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase==
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<StructureSection load='4gmh' size='340' side='right' caption='[[4gmh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='4gmh' size='340' side='right'caption='[[4gmh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gmh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GMH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GMH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mtnN, SAV1599 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 Staphylococcus aureus subsp. aureus Mu50])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gmh OCA], [https://pdbe.org/4gmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gmh RCSB], [https://www.ebi.ac.uk/pdbsum/4gmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gmh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gmh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gmh RCSB], [http://www.ebi.ac.uk/pdbsum/4gmh PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MTNN_STAAM MTNN_STAAM]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).
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[https://www.uniprot.org/uniprot/MTNN_STAAM MTNN_STAAM] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenosylhomocysteine nucleosidase]]
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus mu50]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Anderson, B F]]
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[[Category: Anderson BF]]
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[[Category: Brown, R L]]
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[[Category: Brown RL]]
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[[Category: Evans, G B]]
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[[Category: Evans GB]]
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[[Category: Norris, G E]]
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[[Category: Norris GE]]
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[[Category: Sutherland-Smith, A J]]
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[[Category: Sutherland-Smith AJ]]
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[[Category: Tyler, P C]]
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[[Category: Tyler PC]]
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[[Category: Alpha/beta protein]]
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[[Category: Cleavage]]
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[[Category: Hydrolase]]
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[[Category: Mtan]]
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[[Category: Nucleosidase]]
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[[Category: S-adenosylhomocysteine]]
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Current revision

Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase

PDB ID 4gmh

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