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4gp3
From Proteopedia
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| - | [[Image:4gp3.png|left|200px]] | ||
| - | + | ==The crystal structure of human fascin 1 K358A mutant== | |
| + | <StructureSection load='4gp3' size='340' side='right'caption='[[4gp3]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4gp3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GP3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gp3 OCA], [https://pdbe.org/4gp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gp3 RCSB], [https://www.ebi.ac.uk/pdbsum/4gp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gp3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FSCN1_HUMAN FSCN1_HUMAN] Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.<ref>PMID:9362073</ref> <ref>PMID:9571235</ref> <ref>PMID:20137952</ref> <ref>PMID:20393565</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Fascin|Fascin]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | + | </StructureSection> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Chen | + | [[Category: Large Structures]] |
| - | [[Category: Chen | + | [[Category: Chen L]] |
| - | [[Category: Diaz-Avalos | + | [[Category: Chen S]] |
| - | [[Category: Huang | + | [[Category: Diaz-Avalos R]] |
| - | [[Category: Huang | + | [[Category: Huang FK]] |
| - | [[Category: Huang | + | [[Category: Huang J]] |
| - | [[Category: Jakoncic | + | [[Category: Huang XY]] |
| - | [[Category: Leo-Macias | + | [[Category: Jakoncic J]] |
| - | [[Category: Yang | + | [[Category: Leo-Macias A]] |
| - | [[Category: Zhang | + | [[Category: Yang SY]] |
| - | + | [[Category: Zhang JJ]] | |
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Current revision
The crystal structure of human fascin 1 K358A mutant
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Categories: Homo sapiens | Large Structures | Chen L | Chen S | Diaz-Avalos R | Huang FK | Huang J | Huang XY | Jakoncic J | Leo-Macias A | Yang SY | Zhang JJ
