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8bje
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8bje is ON HOLD Authors: Whittaker, J.J., Guskov, A. Description: Full length structure of the apo-state LpMIP. Category: Unreleased Structures...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==A structure of the truncated LpMIP with bound inhibitor JK236.== | |
| - | + | <StructureSection load='8bje' size='340' side='right'caption='[[8bje]], [[Resolution|resolution]] 1.49Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8bje]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila Legionella pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BJE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=WRL:(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-(hydroxymethyl)-3-[(1~{S})-1-pyridin-2-ylethyl]-3,10-diazabicyclo[4.3.1]decan-2-one'>WRL</scene></td></tr> |
| - | [[Category: Guskov | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bje OCA], [https://pdbe.org/8bje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bje RCSB], [https://www.ebi.ac.uk/pdbsum/8bje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bje ProSAT]</span></td></tr> |
| - | [[Category: Whittaker | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A2S6FAG4_LEGPN A0A2S6FAG4_LEGPN] Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity.[ARBA:ARBA00002861] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Legionella pneumophila]] | ||
| + | [[Category: Goretzki B]] | ||
| + | [[Category: Guskov A]] | ||
| + | [[Category: Hellmich UA]] | ||
| + | [[Category: Whittaker JJ]] | ||
Current revision
A structure of the truncated LpMIP with bound inhibitor JK236.
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