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	<ref name="Ransey">PMID:28504306</ref>		<ref name="Ransey">PMID:28504306</ref>
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		+	Reference for GLP-1R structure.
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		+	<ref name=”Zhang”>PMID:33027691</ref>
	==Function==		==Function==

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Revision as of 14:44, 19 March 2024

GLP-1R Homo Sapiens

spinqualitylabelsall models GLP-1R 6X18 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Contents 1 Introduction 2 Function 3 Structure 4 Active Site 4.1 Binding Interactions of GLP1 4.2 Binding Interactions of Tirzepatide 4.3 Comparison of Binding Interactions 5 Biological/Medical Relevance Introduction Here is a fun paper. [1] Reference for GLP-1R structure. [2] Function Structure Active Site Binding Interactions of GLP1 Figure 1. The coolest image of this protein EVAH!!! Binding Interactions of Tirzepatide Comparison of Binding Interactions Biological/Medical Relevance Type II Diabetes This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

References

1. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
2. ↑ Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D. Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol Cell. 2020 Nov 5;80(3):485-500.e7. PMID:33027691 doi:10.1016/j.molcel.2020.09.020

Student Contributors

• Isabel Kluszynski
• Makenna Marcinek