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8aav
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8aav is ON HOLD until sometime in the future Authors: Boehler, H., Beck, T. Description: Human heavy chain ferritin with introduced Cys residues mo...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Human heavy chain ferritin with introduced Cys residues modified with C10 ligand== | |
| - | + | <StructureSection load='8aav' size='340' side='right'caption='[[8aav]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8aav]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AAV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=O3K:2-bromanyl-N-decyl-ethanamide'>O3K</scene></td></tr> |
| - | [[Category: Beck | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8aav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8aav OCA], [https://pdbe.org/8aav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8aav RCSB], [https://www.ebi.ac.uk/pdbsum/8aav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8aav ProSAT]</span></td></tr> |
| - | [[Category: Boehler | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Beck T]] | ||
| + | [[Category: Boehler H]] | ||
Current revision
Human heavy chain ferritin with introduced Cys residues modified with C10 ligand
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