3ftj

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{{Seed}}
 
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[[Image:3ftj.png|left|200px]]
 
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==Crystal structure of the periplasmic region of MacB from Actinobacillus actinomycetemcomitans==
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The line below this paragraph, containing "STRUCTURE_3ftj", creates the "Structure Box" on the page.
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<StructureSection load='3ftj' size='340' side='right'caption='[[3ftj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ftj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FTJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.999&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ftj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ftj OCA], [https://pdbe.org/3ftj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ftj RCSB], [https://www.ebi.ac.uk/pdbsum/3ftj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ftj ProSAT]</span></td></tr>
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{{STRUCTURE_3ftj| PDB=3ftj | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the periplasmic region of MacB from Actinobacillus actinomycetemcomitans===
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[https://www.uniprot.org/uniprot/MACB_AGGAC MACB_AGGAC] Part of the tripartite efflux system MacAB-TdeA. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.<ref>PMID:19432486</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_19432486}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 19432486 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ft/3ftj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_19432486}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ftj ConSurf].
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3FTJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FTJ OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:19432486</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Aggregatibacter actinomycetemcomitans]]
[[Category: Aggregatibacter actinomycetemcomitans]]
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[[Category: Ha, N C.]]
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[[Category: Large Structures]]
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[[Category: Xu, Y.]]
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[[Category: Ha NC]]
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[[Category: Abc-type transporter]]
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[[Category: Xu Y]]
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[[Category: Antibiotic resistance]]
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[[Category: Atp-binding]]
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[[Category: Cell inner membrane]]
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[[Category: Cell membrane]]
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[[Category: Heat stable exotoxin ii]]
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[[Category: Hydrolase]]
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[[Category: Macrolide-specific pump]]
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[[Category: Membrane]]
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[[Category: Membrane protein]]
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[[Category: Nucleotide-binding]]
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[[Category: Periplasmic region]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 17 08:58:44 2009''
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Current revision

Crystal structure of the periplasmic region of MacB from Actinobacillus actinomycetemcomitans

PDB ID 3ftj

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