This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3fv6
From Proteopedia
(Difference between revisions)
m (Protected "3fv6" [edit=sysop:move=sysop]) |
|||
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3fv6.png|left|200px]] | ||
| - | + | ==Crystal Structure of the CBS domains from the Bacillus subtilis CcpN repressor== | |
| - | + | <StructureSection load='3fv6' size='340' side='right'caption='[[3fv6]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3fv6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FV6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fv6 OCA], [https://pdbe.org/3fv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fv6 RCSB], [https://www.ebi.ac.uk/pdbsum/3fv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fv6 ProSAT]</span></td></tr> |
| - | [[3fv6]] is a 2 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CCPN_BACSU CCPN_BACSU] Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes.<ref>PMID:15720552</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/3fv6_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fv6 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
| - | [[Category: Arold | + | [[Category: Large Structures]] |
| - | [[Category: Chaix | + | [[Category: Arold S]] |
| - | [[Category: Declerck | + | [[Category: Chaix D]] |
| - | [[Category: Hoh | + | [[Category: Declerck N]] |
| - | + | [[Category: Hoh F]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of the CBS domains from the Bacillus subtilis CcpN repressor
| |||||||||||
