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3iip
From Proteopedia
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| - | {{STRUCTURE_3iip| PDB=3iip | SCENE= }} | ||
| - | ===Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series=== | ||
| - | {{ABSTRACT_PUBMED_20036254}} | ||
| - | == | + | ==Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series== |
| - | [[3iip]] is a 6 chain structure with sequence from [ | + | <StructureSection load='3iip' size='340' side='right'caption='[[3iip]], [[Resolution|resolution]] 2.30Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3iip]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IIP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iip OCA], [https://pdbe.org/3iip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iip RCSB], [https://www.ebi.ac.uk/pdbsum/3iip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iip ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/3iip_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iip ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Directed evolution|Directed evolution]] | ||
*[[Kemp eliminase|Kemp eliminase]] | *[[Kemp eliminase|Kemp eliminase]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Dym O]] |
| - | [[Category: | + | [[Category: Khersonsky O]] |
| - | [[Category: | + | [[Category: Tawfik DS]] |
| - | + | ||
Current revision
Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series
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