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3ilf

From Proteopedia

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{{Seed}}
 
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[[Image:3ilf.jpg|left|200px]]
 
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==Crystal structure of porphyranase A (PorA) in complex with neo-porphyrotetraose==
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The line below this paragraph, containing "STRUCTURE_3ilf", creates the "Structure Box" on the page.
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<StructureSection load='3ilf' size='340' side='right'caption='[[3ilf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ilf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zobellia_galactanivorans Zobellia galactanivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ILF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ILF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=L6S:6-O-SULFO-ALPHA-L-GALACTOSE'>L6S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3ilf| PDB=3ilf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ilf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ilf OCA], [https://pdbe.org/3ilf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ilf RCSB], [https://www.ebi.ac.uk/pdbsum/3ilf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ilf ProSAT]</span></td></tr>
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</table>
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===Crystal structure of porphyranase A (PorA) in complex with neo-porphyrotetraose===
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== Function ==
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[https://www.uniprot.org/uniprot/PORA_ZOBGA PORA_ZOBGA] Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6-sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6-sulfate-(1->3)-beta-D-galactose. Some longer oligosaccharides of even number of residues are also observed. Inactive on the non-sulfated agarose portion of the porphyran backbone. Displays a strict requirement for C6-sulfate in the -2 and +1-binding subsites.<ref>PMID:20376150</ref> <ref>PMID:22778272</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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3ILF is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zobellia_galactanivorans Zobellia galactanivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ILF OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/il/3ilf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ilf ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Zobellia galactanivorans]]
[[Category: Zobellia galactanivorans]]
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[[Category: Barbeyron, T.]]
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[[Category: Barbeyron T]]
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[[Category: Correc, G.]]
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[[Category: Correc G]]
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[[Category: Czjzek, M.]]
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[[Category: Czjzek M]]
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[[Category: Hehemann, J H.]]
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[[Category: Hehemann JH]]
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[[Category: Helbert, W.]]
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[[Category: Helbert W]]
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[[Category: Michel, G.]]
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[[Category: Michel G]]
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[[Category: Beta-sandwich fold]]
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[[Category: Glycoside hydrolase family gh16]]
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[[Category: Hydrolase-carbohydrate complex]]
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[[Category: Jelly roll]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:47:37 2010''
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Current revision

Crystal structure of porphyranase A (PorA) in complex with neo-porphyrotetraose

PDB ID 3ilf

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