This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3u57
From Proteopedia
(Difference between revisions)
m (Protected "3u57" [edit=sysop:move=sysop]) |
|||
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity== | |
| + | <StructureSection load='3u57' size='340' side='right'caption='[[3u57]], [[Resolution|resolution]] 2.43Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3u57]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U57 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.43Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DH8:(2BETA,7BETA,16S,17R,19E,21BETA)-21-(BETA-D-GLUCOPYRANOSYLOXY)-2,7-DIHYDRO-7,17-CYCLOSARPAGAN-17-YL+ACETATE'>DH8</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u57 OCA], [https://pdbe.org/3u57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u57 RCSB], [https://www.ebi.ac.uk/pdbsum/3u57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u57 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RG1_RAUSE RG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the treatment of heart disorders.<ref>PMID:10975500</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rauvolfia serpentina]] | ||
| + | [[Category: Barleben L]] | ||
| + | [[Category: Lin H]] | ||
| + | [[Category: Panjikar S]] | ||
| + | [[Category: Rajendran C]] | ||
| + | [[Category: Ruppert M]] | ||
| + | [[Category: Stoeckigt J]] | ||
| + | [[Category: Wang M]] | ||
| + | [[Category: Xia L]] | ||
Current revision
Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
| |||||||||||
Categories: Large Structures | Rauvolfia serpentina | Barleben L | Lin H | Panjikar S | Rajendran C | Ruppert M | Stoeckigt J | Wang M | Xia L
