This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3uo8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:38, 20 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3uo8.png|left|200px]]
 
-
<!--
+
==Crystal structure of the MALT1 paracaspase (P1 form)==
-
The line below this paragraph, containing "STRUCTURE_3uo8", creates the "Structure Box" on the page.
+
<StructureSection load='3uo8' size='340' side='right'caption='[[3uo8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3uo8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UO8 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CF0:FLUOROMETHANE'>CF0</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene></td></tr>
-
{{STRUCTURE_3uo8| PDB=3uo8 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uo8 OCA], [https://pdbe.org/3uo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uo8 RCSB], [https://www.ebi.ac.uk/pdbsum/3uo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uo8 ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of the MALT1 paracaspase (P1 form)===
+
== Disease ==
-
 
+
[https://www.uniprot.org/uniprot/MALT1_HUMAN MALT1_HUMAN] Note=A chromosomal aberration involving MALT1 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with BIRC2. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma.
-
 
+
== Function ==
-
<!--
+
[https://www.uniprot.org/uniprot/MALT1_HUMAN MALT1_HUMAN] Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.<ref>PMID:11262391</ref> <ref>PMID:14695475</ref> <ref>PMID:18264101</ref>
-
The line below this paragraph, {{ABSTRACT_PUBMED_22158899}}, adds the Publication Abstract to the page
+
== References ==
-
(as it appears on PubMed at http://www.pubmed.gov), where 22158899 is the PubMed ID number.
+
<references/>
-
-->
+
__TOC__
-
{{ABSTRACT_PUBMED_22158899}}
+
</StructureSection>
-
 
+
-
==About this Structure==
+
-
[[3uo8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UO8 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:022158899</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Jeffrey, P D.]]
+
[[Category: Large Structures]]
-
[[Category: Shi, Y.]]
+
[[Category: Jeffrey PD]]
-
[[Category: Yu, J W.]]
+
[[Category: Shi Y]]
-
[[Category: Caspase fold]]
+
[[Category: Yu JW]]
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Immunoglobulin fold]]
+
-
[[Category: Lymphoma]]
+
-
[[Category: Nf-kb signalling]]
+
-
[[Category: Paracaspase]]
+

Current revision

Crystal structure of the MALT1 paracaspase (P1 form)

PDB ID 3uo8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3uo8"
Personal tools