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4jgv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human Nur77 Ligand-binding Domain in Complex with THPN== | |
| - | + | <StructureSection load='4jgv' size='340' side='right'caption='[[4jgv]], [[Resolution|resolution]] 3.01Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4jgv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JGV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=T94:1-(3,4,5-TRIHYDROXYPHENYL)NONAN-1-ONE'>T94</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jgv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jgv OCA], [https://pdbe.org/4jgv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jgv RCSB], [https://www.ebi.ac.uk/pdbsum/4jgv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jgv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen H]] | ||
| + | [[Category: Li A]] | ||
| + | [[Category: Li F]] | ||
| + | [[Category: Lin T]] | ||
| + | [[Category: Tian X]] | ||
| + | [[Category: Wan W]] | ||
| + | [[Category: Wan Y]] | ||
| + | [[Category: Wu Q]] | ||
| + | [[Category: Xing Y]] | ||
| + | [[Category: Zhang Q]] | ||
Current revision
Crystal Structure of Human Nur77 Ligand-binding Domain in Complex with THPN
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Categories: Homo sapiens | Large Structures | Chen H | Li A | Li F | Lin T | Tian X | Wan W | Wan Y | Wu Q | Xing Y | Zhang Q
