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4jnd
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| - | {{STRUCTURE_4jnd| PDB=4jnd | SCENE= }} | ||
| - | ===Structure of a C.elegans sex determining protein=== | ||
| - | == | + | ==Structure of a C.elegans sex determining protein== |
| - | [[http://www.uniprot.org/uniprot/FEM2_CAEEL FEM2_CAEEL | + | <StructureSection load='4jnd' size='340' side='right'caption='[[4jnd]], [[Resolution|resolution]] 1.65Å' scene=''> |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4jnd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JND OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JND FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.652Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jnd OCA], [https://pdbe.org/4jnd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jnd RCSB], [https://www.ebi.ac.uk/pdbsum/4jnd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jnd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FEM2_CAEEL FEM2_CAEEL] Probable phosphatase involved in the regulation of sex determination. Plays an important role in regulating a pathway transducing a non-cell-autonomous signal to a nuclear transcription factor. Promotes apoptosis. Together with fem-3 associates with the CBC(fem-1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tra-1. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Feng | + | [[Category: Feng Y]] |
| - | [[Category: Ge | + | [[Category: Ge J]] |
| - | [[Category: Yang | + | [[Category: Yang M]] |
| - | [[Category: Zhang | + | [[Category: Zhang Y]] |
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Current revision
Structure of a C.elegans sex determining protein
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