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4k5a

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{{STRUCTURE_4k5a| PDB=4k5a | SCENE= }}
 
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===Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W===
 
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==Function==
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==Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W==
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[[http://www.uniprot.org/uniprot/B2CL2_BOVIN B2CL2_BOVIN]] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity).
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<StructureSection load='4k5a' size='340' side='right'caption='[[4k5a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4k5a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K5A FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5a OCA], [https://pdbe.org/4k5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k5a RCSB], [https://www.ebi.ac.uk/pdbsum/4k5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5a ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/B2CL2_BOVIN B2CL2_BOVIN] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity).
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==About this Structure==
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==See Also==
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[[4k5a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5A OCA].
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*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]]
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[[Category: Plueckthun, A.]]
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__TOC__
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[[Category: Sauer, E.]]
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</StructureSection>
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[[Category: Schilling, J.]]
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[[Category: Bos taurus]]
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[[Category: Schoeppe, J.]]
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[[Category: Escherichia coli]]
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[[Category: Anti-apoptotic bcl-2 family]]
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[[Category: Large Structures]]
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[[Category: Apoptosis]]
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[[Category: Plueckthun A]]
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[[Category: Bcl-w]]
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[[Category: Sauer E]]
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[[Category: Crystal structure]]
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[[Category: Schilling J]]
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[[Category: Darpin]]
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[[Category: Schoeppe J]]
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[[Category: Ligand binding-competent conformation]]
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Current revision

Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W

PDB ID 4k5a

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