4ml0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4ml0 is ON HOLD Authors: Liang, Y.J., Gao, Z.Q., Liu, Q.S., Dong, Y.H. Description: Crystal structure of E.coli DinJ-YafQ complex) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of E.coli DinJ-YafQ complex== | |
| - | + | <StructureSection load='4ml0' size='340' side='right'caption='[[4ml0]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ml0]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_B_str._REL606 Escherichia coli B str. REL606]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ML0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ML0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ml0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ml0 OCA], [https://pdbe.org/4ml0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ml0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ml0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ml0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DINJ_ECOBD DINJ_ECOBD] Antitoxin component of a type II toxin-antitoxin (TA) system (PubMed:24923448). A labile antitoxin that counteracts the effect of cognate toxin YafQ (PubMed:24923448). The YafQ-DinJ heterotetramer binds the consensus sequence 5'-TTTGAGCTACA-3' in the dinJ promoter; DinJ also binds DNA but not as well as the YafQ-DinJ complex (PubMed:24923448). Binding to the dinJ represses expression of the promoter (By similarity).[UniProtKB:Q47150]<ref>PMID:24923448</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli B str. REL606]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dong YH]] | ||
| + | [[Category: Gao ZQ]] | ||
| + | [[Category: Liang YJ]] | ||
| + | [[Category: Liu QS]] | ||
Current revision
Crystal structure of E.coli DinJ-YafQ complex
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