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4x5m
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of SemiSWEET in the inward-open conformation== | |
| - | + | <StructureSection load='4x5m' size='340' side='right'caption='[[4x5m]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4x5m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_UMEA_3162-1 Escherichia coli UMEA 3162-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X5M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5m OCA], [https://pdbe.org/4x5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x5m RCSB], [https://www.ebi.ac.uk/pdbsum/4x5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x5m ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SWEET_ECOU3 SWEET_ECOU3] The homodimer mediates transmembrane sugar transport down a concentration gradient. Transport is probably effected by rocking-type movements, where a cargo-binding cavity opens first on one and then on the other side of the membrane.<ref>PMID:25598322</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli UMEA 3162-1]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ishitani R]] | ||
| + | [[Category: Lee Y]] | ||
| + | [[Category: Nishizawa T]] | ||
| + | [[Category: Nureki O]] | ||
| + | [[Category: Yamashita K]] | ||
Current revision
Crystal structure of SemiSWEET in the inward-open conformation
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