This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4xdv
From Proteopedia
(Difference between revisions)
m (Protected "4xdv" [edit=sysop:move=sysop]) |
|||
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH complexed with cyclohexanediol== | |
| + | <StructureSection load='4xdv' size='340' side='right'caption='[[4xdv]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4xdv]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XDV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=40O:(1R,2R)-CYCLOHEXANE-1,2-DIOL'>40O</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xdv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xdv OCA], [https://pdbe.org/4xdv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xdv RCSB], [https://www.ebi.ac.uk/pdbsum/4xdv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xdv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates. | ||
| - | + | ==See Also== | |
| - | + | *[[Epoxide hydrolase 3D structures|Epoxide hydrolase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Rhodococcus erythropolis]] |
| - | [[Category: | + | [[Category: Kong XD]] |
| - | [[Category: | + | [[Category: Lonsdale R]] |
| - | [[Category: | + | [[Category: Reetz MT]] |
| - | [[Category: Zhou | + | [[Category: Sun Z]] |
| + | [[Category: Xu JH]] | ||
| + | [[Category: Zhou J]] | ||
Current revision
Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH complexed with cyclohexanediol
| |||||||||||
Categories: Large Structures | Rhodococcus erythropolis | Kong XD | Lonsdale R | Reetz MT | Sun Z | Xu JH | Zhou J
