4xgq
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of addiction module from Mycobacterial species== | |
- | + | <StructureSection load='4xgq' size='340' side='right'caption='[[4xgq]], [[Resolution|resolution]] 2.70Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4xgq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XGQ FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xgq OCA], [https://pdbe.org/4xgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xgq RCSB], [https://www.ebi.ac.uk/pdbsum/4xgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xgq ProSAT]</span></td></tr> |
- | [[Category: Lee | + | </table> |
- | [[Category: Lee | + | == Function == |
+ | [https://www.uniprot.org/uniprot/VPC30_MYCTU VPC30_MYCTU] Toxic component of a type II toxin-antitoxin (TA) module. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB30.[HAMAP-Rule:MF_00265]<ref>PMID:20011113</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
+ | [[Category: Lee B-J]] | ||
+ | [[Category: Lee I-G]] | ||
+ | [[Category: Lee SJ]] |
Current revision
Crystal structure of addiction module from Mycobacterial species
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