4xo2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:02, 20 March 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==crystal structure of GnsA from E.coli==
==crystal structure of GnsA from E.coli==
-
<StructureSection load='4xo2' size='340' side='right' caption='[[4xo2]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
+
<StructureSection load='4xo2' size='340' side='right'caption='[[4xo2]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4xo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XO2 FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xo1|4xo1]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.952&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [http://pdbe.org/4xo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [http://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo2 OCA], [https://pdbe.org/4xo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xo2 RCSB], [https://www.ebi.ac.uk/pdbsum/4xo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xo2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/GNSA_ECOLI GNSA_ECOLI]] Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.<ref>PMID:11544213</ref>
+
[https://www.uniprot.org/uniprot/GNSA_ECOLI GNSA_ECOLI] Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.<ref>PMID:11544213</ref>
-
<div style="background-color:#fffaf0;">
+
-
== Publication Abstract from PubMed ==
+
-
Escherichia Coli GnsA is a regulator of phosphatidylethanolamine synthesis and functions as a suppressor of both a secG null mutation and fabA6 mutations. GnsA may also be a toxin with the cognate antitoxin YmcE. Here we report the crystal structure of GnsA to 1.8 A. GnsA forms a V shaped hairpin structure that is tightly associated into a homodimer. Our comprehensive structural study suggests that GnsA is structurally similar to an outer membrane protein, suggesting a function of protein binding.
+
-
 
+
-
Crystal structure of GnsA from Escherichia coli.,Wei Y, Zhan L, Gao Z, Prive GG, Dong Y Biochem Biophys Res Commun. 2015 Jun 19;462(1):1-7. doi:, 10.1016/j.bbrc.2015.03.133. Epub 2015 Apr 1. PMID:25839658<ref>PMID:25839658</ref>
+
-
 
+
-
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+
-
</div>
+
-
<div class="pdbe-citations 4xo2" style="background-color:#fffaf0;"></div>
+
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Dong, Y H]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Gao, Z Q]]
+
[[Category: Large Structures]]
-
[[Category: Wei, Y]]
+
[[Category: Dong YH]]
-
[[Category: Zhan, L H]]
+
[[Category: Gao ZQ]]
-
[[Category: Suppressor]]
+
[[Category: Wei Y]]
 +
[[Category: Zhan LH]]

Current revision

crystal structure of GnsA from E.coli

PDB ID 4xo2

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4xo2"
Personal tools