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4ysw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of rat xanthine oxidoreductase, C-terminal deletion protein variant, NADH bound form== | |
| + | <StructureSection load='4ysw' size='340' side='right'caption='[[4ysw]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4ysw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YSW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=URC:URIC+ACID'>URC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ysw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ysw OCA], [https://pdbe.org/4ysw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ysw RCSB], [https://www.ebi.ac.uk/pdbsum/4ysw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ysw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/XDH_RAT XDH_RAT] Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species.<ref>PMID:17301076</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Xanthine dehydrogenase 3D structures|Xanthine dehydrogenase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Kawaguchi | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Nishino | + | [[Category: Rattus norvegicus]] |
| - | [[Category: Okamoto | + | [[Category: Eger BT]] |
| - | [[Category: | + | [[Category: Kawaguchi Y]] |
| + | [[Category: Matsumura T]] | ||
| + | [[Category: Nishino T]] | ||
| + | [[Category: Okamoto K]] | ||
| + | [[Category: Pai EF]] | ||
Current revision
Structure of rat xanthine oxidoreductase, C-terminal deletion protein variant, NADH bound form
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