This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5axa
From Proteopedia
(Difference between revisions)
m (Protected "5axa" [edit=sysop:move=sysop]) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse SAHH complexed with adenosine== | |
| - | + | <StructureSection load='5axa' size='340' side='right'caption='[[5axa]], [[Resolution|resolution]] 1.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5axa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AXA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> |
| - | [[Category: Ishihara | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5axa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5axa OCA], [https://pdbe.org/5axa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5axa RCSB], [https://www.ebi.ac.uk/pdbsum/5axa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5axa ProSAT]</span></td></tr> |
| - | [[Category: Kusakabe | + | </table> |
| - | [[Category: Tanaka | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SAHH_MOUSE SAHH_MOUSE] Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Ishihara M]] | ||
| + | [[Category: Kusakabe Y]] | ||
| + | [[Category: Tanaka N]] | ||
Current revision
Crystal structure of mouse SAHH complexed with adenosine
| |||||||||||
