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5ci9
From Proteopedia
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==Crystal structure of human Tob in complex with inhibitor fragment 6== | ==Crystal structure of human Tob in complex with inhibitor fragment 6== | ||
| - | <StructureSection load='5ci9' size='340' side='right' caption='[[5ci9]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='5ci9' size='340' side='right'caption='[[5ci9]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ci9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CI9 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5ci9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CI9 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=549:1-(PROPAN-2-YL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC+ACID'>549</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=549:1-(PROPAN-2-YL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC+ACID'>549</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ci9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ci9 OCA], [https://pdbe.org/5ci9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ci9 RCSB], [https://www.ebi.ac.uk/pdbsum/5ci9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ci9 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Bai Y]] |
| - | [[Category: | + | [[Category: Bartlam M]] |
| - | [[Category: | + | [[Category: Nagatoishi S]] |
| - | [[Category: | + | [[Category: Suzuki T]] |
| - | [[Category: | + | [[Category: Tashiro S]] |
| - | [[Category: | + | [[Category: Tsumoto K]] |
| - | [[Category: | + | [[Category: Yamamoto T]] |
Current revision
Crystal structure of human Tob in complex with inhibitor fragment 6
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Categories: Homo sapiens | Large Structures | Bai Y | Bartlam M | Nagatoishi S | Suzuki T | Tashiro S | Tsumoto K | Yamamoto T
