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5gi4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==DEAD-box RNA helicase== | |
| + | <StructureSection load='5gi4' size='340' side='right'caption='[[5gi4]], [[Resolution|resolution]] 2.24Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5gi4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GI4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.244Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gi4 OCA], [https://pdbe.org/5gi4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gi4 RCSB], [https://www.ebi.ac.uk/pdbsum/5gi4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gi4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DEAD_ECOLI DEAD_ECOLI] DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity at low temperature. Involved in 50S ribosomal subunit assembly, acting after SrmB, and could also play a role in the biogenesis of the 30S ribosomal subunit. In addition, is involved in mRNA decay, via formation of a cold-shock degradosome with RNase E. Also stimulates translation of some mRNAs, probably at the level of initiation.[HAMAP-Rule:MF_00964]<ref>PMID:10216955</ref> <ref>PMID:15148362</ref> <ref>PMID:15196029</ref> <ref>PMID:15554978</ref> <ref>PMID:17259309</ref> <ref>PMID:8552679</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Helicase 3D structures|Helicase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Li F]] | ||
| + | [[Category: Shi Y]] | ||
| + | [[Category: Wang L]] | ||
| + | [[Category: Wu L]] | ||
| + | [[Category: Xu L]] | ||
Current revision
DEAD-box RNA helicase
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Categories: Escherichia coli K-12 | Large Structures | Li F | Shi Y | Wang L | Wu L | Xu L
