This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5i2l
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of EF-hand containing protein== | |
| - | + | <StructureSection load='5i2l' size='340' side='right'caption='[[5i2l]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5i2l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5I2L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5i2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i2l OCA], [https://pdbe.org/5i2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5i2l RCSB], [https://www.ebi.ac.uk/pdbsum/5i2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5i2l ProSAT]</span></td></tr> |
| - | [[Category: Cheong | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/EFHD2_HUMAN EFHD2_HUMAN] May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Kwon | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: An JY]] |
| - | [[Category: | + | [[Category: Cheong H]] |
| - | [[Category: | + | [[Category: Eom SH]] |
| - | [[Category: | + | [[Category: Jun C]] |
| - | [[Category: | + | [[Category: Kang JY]] |
| - | [[Category: Song | + | [[Category: Kim TG]] |
| - | [[Category: | + | [[Category: Kwon MS]] |
| + | [[Category: Lee JG]] | ||
| + | [[Category: Lee SH]] | ||
| + | [[Category: Lee Y]] | ||
| + | [[Category: Lim JJ]] | ||
| + | [[Category: Park JS]] | ||
| + | [[Category: Park KR]] | ||
| + | [[Category: Song WK]] | ||
| + | [[Category: Youn HS]] | ||
Current revision
Structure of EF-hand containing protein
| |||||||||||
