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6on2

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(New page: ==Lon Protease from Yersinia pestis with Y2853 substrate== <StructureSection load='6on2' size='340' side='right'caption='6on2, resolution 3.00&Aring;' scene=''> == Stru...)
Current revision (09:24, 20 March 2024) (edit) (undo)
 
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==Lon Protease from Yersinia pestis with Y2853 substrate==
==Lon Protease from Yersinia pestis with Y2853 substrate==
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<StructureSection load='6on2' size='340' side='right'caption='[[6on2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<SX load='6on2' size='340' side='right' viewer='molstar' caption='[[6on2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6on2]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ON2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ON2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6on2]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ON2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ON2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_La Endopeptidase La], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.53 3.4.21.53] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6on2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6on2 OCA], [http://pdbe.org/6on2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6on2 RCSB], [http://www.ebi.ac.uk/pdbsum/6on2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6on2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6on2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6on2 OCA], [https://pdbe.org/6on2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6on2 RCSB], [https://www.ebi.ac.uk/pdbsum/6on2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6on2 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A5P8YJ65_YERPE A0A5P8YJ65_YERPE] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.[HAMAP-Rule:MF_01973]
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Endopeptidase La]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Adjei, E]]
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[[Category: Yersinia pestis]]
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[[Category: Asmita, A]]
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[[Category: Adjei E]]
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[[Category: Karzai, A W]]
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[[Category: Asmita A]]
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[[Category: Lander, G C]]
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[[Category: Karzai AW]]
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[[Category: Puchades, C]]
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[[Category: Lander GC]]
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[[Category: Shin, M]]
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[[Category: Puchades C]]
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[[Category: Wiseman, R L]]
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[[Category: Shin M]]
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[[Category: Aaa+]]
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[[Category: Wiseman RL]]
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[[Category: Atpase]]
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[[Category: Hydrolase]]
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[[Category: Lon]]
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[[Category: Mitochondrial protease]]
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Current revision

Lon Protease from Yersinia pestis with Y2853 substrate

6on2, resolution 3.00Å

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