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1dee

From Proteopedia

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{{Seed}}
 
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[[Image:1dee.png|left|200px]]
 
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==Structure of S. aureus protein A bound to a human IgM Fab==
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The line below this paragraph, containing "STRUCTURE_1dee", creates the "Structure Box" on the page.
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<StructureSection load='1dee' size='340' side='right'caption='[[1dee]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1dee]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DEE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dee OCA], [https://pdbe.org/1dee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dee RCSB], [https://www.ebi.ac.uk/pdbsum/1dee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dee ProSAT]</span></td></tr>
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{{STRUCTURE_1dee| PDB=1dee | SCENE= }}
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</table>
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== Function ==
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===CRYSTAL STRUCTURE AT 2.7A RESOLUTION OF A COMPLEX BETWEEN A STAPHYLOCOCCUS AUREUS DOMAIN AND A FAB FRAGMENT OF A HUMAN IGM ANTIBODY===
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[https://www.uniprot.org/uniprot/SPA_STAA8 SPA_STAA8]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_10805799}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 10805799 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/1dee_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_10805799}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dee ConSurf].
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1DEE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DEE OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity., Graille M, Stura EA, Corper AL, Sutton BJ, Taussig MJ, Charbonnier JB, Silverman GJ, Proc Natl Acad Sci U S A. 2000 May 9;97(10):5399-404. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10805799 10805799]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Charbonnier, J B.]]
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[[Category: Charbonnier JB]]
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[[Category: Corper, A L.]]
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[[Category: Corper AL]]
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[[Category: Graille, M.]]
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[[Category: Graille M]]
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[[Category: Silverman, G J.]]
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[[Category: Silverman GJ]]
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[[Category: Stura, E A.]]
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[[Category: Stura EA]]
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[[Category: Sutton, B J.]]
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[[Category: Sutton BJ]]
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[[Category: Taussig, M J.]]
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[[Category: Taussig MJ]]
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[[Category: Fab-ibp complex crystal structure 2 7a resolution binding outside the antigen combining site superantigen fab vh3 specificity]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:54:03 2008''
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Current revision

Structure of S. aureus protein A bound to a human IgM Fab

PDB ID 1dee

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