1dje

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[[Image:1dje.png|left|200px]]
 
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{{STRUCTURE_1dje| PDB=1dje | SCENE= }}
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==CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF 8-AMINO-7-OXONANOATE SYNTHASE==
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<StructureSection load='1dje' size='340' side='right'caption='[[1dje]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF 8-AMINO-7-OXONANOATE SYNTHASE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1dje]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DJE FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10642176}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dje OCA], [https://pdbe.org/1dje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dje RCSB], [https://www.ebi.ac.uk/pdbsum/1dje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dje ProSAT]</span></td></tr>
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[[1dje]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJE OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/BIOF_ECOLI BIOF_ECOLI] Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate, but it is believed that pimeloyl-ACP rather than pimeloyl-CoA is the physiological substrate of BioF.<ref>PMID:20693992</ref>
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<ref group="xtra">PMID:010642176</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Category: 8-amino-7-oxononanoate synthase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dj/1dje_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dje ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Alexeev, D.]]
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[[Category: Large Structures]]
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[[Category: Alexeeva, M.]]
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[[Category: Alexeev D]]
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[[Category: Baxter, R L.]]
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[[Category: Alexeeva M]]
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[[Category: Campopiano, D J.]]
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[[Category: Baxter RL]]
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[[Category: Sawyer, L.]]
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[[Category: Campopiano DJ]]
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[[Category: Watt, R M.]]
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[[Category: Sawyer L]]
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[[Category: Webster, S P.]]
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[[Category: Watt RM]]
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[[Category: 8-amino-7-ketopelargonate synthase]]
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[[Category: Webster SP]]
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[[Category: 8-amino-7-oxonanoate synthase]]
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[[Category: Biotin biosynthesis]]
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[[Category: Transferase]]
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Current revision

CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF 8-AMINO-7-OXONANOATE SYNTHASE

PDB ID 1dje

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