This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1djp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:50, 20 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1djp.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE WITH THE INHIBITOR DON COVALENTLY BOUND IN THE ACTIVE SITE==
-
The line below this paragraph, containing "STRUCTURE_1djp", creates the "Structure Box" on the page.
+
<StructureSection load='1djp' size='340' side='right'caption='[[1djp]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1djp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._7A Pseudomonas sp. 7A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DJP FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DO2:5,5-DIHYDROXY-6-OXO-L-NORLEUCINE'>DO2</scene></td></tr>
-
{{STRUCTURE_1djp| PDB=1djp | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1djp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1djp OCA], [https://pdbe.org/1djp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1djp RCSB], [https://www.ebi.ac.uk/pdbsum/1djp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1djp ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ASPQ_PSES7 ASPQ_PSES7]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dj/1djp_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1djp ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE WITH THE INHIBITOR DON COVALENTLY BOUND IN THE ACTIVE SITE===
+
==See Also==
-
 
+
*[[Glutaminase 3D structures|Glutaminase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_10684596}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 10684596 is the PubMed ID number.
+
[[Category: Pseudomonas sp. 7A]]
-
-->
+
[[Category: Lacount MW]]
-
{{ABSTRACT_PUBMED_10684596}}
+
[[Category: Lebioda L]]
-
 
+
[[Category: Lewinski K]]
-
==About this Structure==
+
[[Category: Ortlund E]]
-
1DJP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJP OCA].
+
-
 
+
-
==Reference==
+
-
Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu., Ortlund E, Lacount MW, Lewinski K, Lebioda L, Biochemistry. 2000 Feb 15;39(6):1199-204. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10684596 10684596]
+
-
[[Category: Pseudomonas sp.]]
+
-
[[Category: Single protein]]
+
-
[[Category: Lacount, M W.]]
+
-
[[Category: Lebioda, L.]]
+
-
[[Category: Lewinski, K.]]
+
-
[[Category: Ortlund, E.]]
+
-
[[Category: 6-diazo-5-oxo-l-norvaline]]
+
-
[[Category: Asparaginase]]
+
-
[[Category: Covalently bound inhibitor]]
+
-
[[Category: Don]]
+
-
[[Category: Glutaminase]]
+
-
[[Category: Glutaminase-asparaginase]]
+
-
[[Category: Pga]]
+
-
[[Category: Suicide inhibitor]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:10:12 2008''
+

Current revision

CRYSTAL STRUCTURE OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE WITH THE INHIBITOR DON COVALENTLY BOUND IN THE ACTIVE SITE

PDB ID 1djp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1djp"
Personal tools