This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1dpx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:52, 20 March 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1dpx.jpg|left|200px]]
 
-
<!--
+
==STRUCTURE OF HEN EGG-WHITE LYSOZYME==
-
The line below this paragraph, containing "STRUCTURE_1dpx", creates the "Structure Box" on the page.
+
<StructureSection load='1dpx' size='340' side='right'caption='[[1dpx]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1dpx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPX FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-
{{STRUCTURE_1dpx| PDB=1dpx | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpx OCA], [https://pdbe.org/1dpx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpx RCSB], [https://www.ebi.ac.uk/pdbsum/1dpx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpx ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/1dpx_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dpx ConSurf].
 +
<div style="clear:both"></div>
-
'''STRUCTURE OF HEN EGG-WHITE LYSOZYME'''
+
==See Also==
-
 
+
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
-
 
+
== References ==
-
==Overview==
+
<references/>
-
Hen egg-white lysozyme has been crystallized at slightly alkaline pH using 2-methyl-2,4-pentanediol (MPD) as the precipitant. The crystals are nearly isomorphous to crystals grown at acidic pH using sodium chloride as the precipitant. However, the growth kinetics differ markedly between the two conditions. The major reason for this is a molecule of MPD that binds tightly in between two lysozyme molecules and favors the growth of the crystals along the crystallographic c direction over growth perpendicular to it.
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
1DPX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPX OCA].
+
-
 
+
-
==Reference==
+
-
Crystallization, structure solution and refinement of hen egg-white lysozyme at pH 8.0 in the presence of MPD., Weiss MS, Palm GJ, Hilgenfeld R, Acta Crystallogr D Biol Crystallogr. 2000 Aug;56(Pt 8):952-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10944331 10944331]
+
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
-
[[Category: Lysozyme]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Hilgenfeld R]]
-
[[Category: Hilgenfeld, R.]]
+
[[Category: Palm GJ]]
-
[[Category: Palm, G J.]]
+
[[Category: Weiss MS]]
-
[[Category: Weiss, M S.]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Protein-chloride complex]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 14:08:07 2008''
+

Current revision

STRUCTURE OF HEN EGG-WHITE LYSOZYME

PDB ID 1dpx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1dpx"
Personal tools