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1dty

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[[Image:1dty.gif|left|200px]]<br /><applet load="1dty" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1dty, resolution 2.14&Aring;" />
 
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'''CRYSTAL STRUCTURE OF ADENOSYLMETHIONINE-8-AMINO-7-OXONANOATE AMINOTRANSFERASE WITH PYRIDOXAL PHOSPHATE COFACTOR.'''<br />
 
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==About this Structure==
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==CRYSTAL STRUCTURE OF ADENOSYLMETHIONINE-8-AMINO-7-OXONANOATE AMINOTRANSFERASE WITH PYRIDOXAL PHOSPHATE COFACTOR.==
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1DTY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=PLP:'>PLP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenosylmethionine--8-amino-7-oxononanoate_transaminase Adenosylmethionine--8-amino-7-oxononanoate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.62 2.6.1.62] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTY OCA].
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<StructureSection load='1dty' size='340' side='right'caption='[[1dty]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
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[[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]]
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== Structural highlights ==
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[[Category: Escherichia coli]]
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<table><tr><td colspan='2'>[[1dty]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DTY FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
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[[Category: Alexeev, D.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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[[Category: Alexeeva, M V.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dty OCA], [https://pdbe.org/1dty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dty RCSB], [https://www.ebi.ac.uk/pdbsum/1dty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dty ProSAT]</span></td></tr>
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[[Category: Baxter, R L.]]
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</table>
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[[Category: Campopiano, D.]]
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== Function ==
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[[Category: Sawyer, L.]]
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[https://www.uniprot.org/uniprot/BIOA_ECOLI BIOA_ECOLI] Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.<ref>PMID:1092681</ref>
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[[Category: NA]]
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== Evolutionary Conservation ==
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[[Category: PLP]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: biotin biosynthesis]]
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Check<jmol>
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[[Category: dapa]]
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<jmolCheckbox>
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[[Category: diaminonanonoic acid]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/1dty_consurf.spt"</scriptWhenChecked>
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[[Category: diaminopelargonic acid]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dty ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:20:31 2008''
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==See Also==
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*[[7%2C8-diaminopelargonic acid synthase 3D structures|7%2C8-diaminopelargonic acid synthase 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Alexeev D]]
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[[Category: Alexeeva MV]]
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[[Category: Baxter RL]]
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[[Category: Campopiano D]]
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[[Category: Sawyer L]]

Current revision

CRYSTAL STRUCTURE OF ADENOSYLMETHIONINE-8-AMINO-7-OXONANOATE AMINOTRANSFERASE WITH PYRIDOXAL PHOSPHATE COFACTOR.

PDB ID 1dty

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